Roles of Membrane Contact Sites in Organelle Dynamics and Diseases

Results of the research

Paper Presentation

2014

Shigeru Yanagi, Shun Nagashima

1.
Saida, H., Matsuzaki, Y., Takayama, K., Iizuka, A., Konno, A., Yanagi, S., and Hirai, H. One-year follow-up of transgene expression by integrase-defective lentiviral vectors and their therapeutic potential in spinocerebellar ataxia model mice. Gene Ther 1(9), 820-827 (2014) [PubMed]
2.
Homma, M., Nagashima, S., Fukuda, T., Yanagi, S., Miyakawa, H., Suzuki, E., and Morimoto, T. Downregulation of Centaurin gamma1A increases synaptic transmission at Drosophila larval neuromuscular junctions. Eur. J. Neurosci. 40(8), 3158-3170 (2014) [PubMed]

Mitsuo Tagaya, Kohei Arasaki

1.
Arasaki, K., Shimizu, H., Mogari, H., Nishida, N., Hirota, N., Furuno, A., Kudo, Y., Baba, M., Baba, N., Cheng, J., Fujimoto, T., Ishihara, N., Ortiz-Sandoval, C., Barlow, L. D., Raturi, A., Dohmae, N., Wakana, Y., Inoue, H., Tani, K., Dacks, J. B., Simmen, T., and Tagaya, M. Role for the ancient SNARE syntaxin 17 in regulating mitochondrial division. Dev. Cell 32, 304-317 (2015) [PubMed]
2.
Noda, C., Kimura, H., Arasaki, K., Matsushita, M., Yamamoto, A., Wakana, Y., Inoue, H., and Tagaya, M. Valosin-containing protein-interacting membrane protein (VIMP) links the endoplasmic reticulum with microtubules in concert with cytoskeleton-linking membrane protein (CLIMP)-63. J. Biol. Chem. 289, 24304-24313 (2014). [PubMed]

Katsuko Tani, Takashi Baba

1.
Doi, H., Ushiyama, M., Baba, T., Tani, K., Shiina, M., Ogata, K., Miyatake, S., Fukuda-Yuzawa, Y., Tsuji, S., Nakashima, M., Tsurusaki, Y., Miyake, N., Saitsu, H., Ikeda, S., Tanaka, F., Matsumoto, N., and Yoshida, K. Late-onset spastic ataxia phenotype in a patient with a homozygous DDHD2 mutation. Sci. Rep. 4, 7132 (2014) [PubMed]
2.
Arasaki, K., Shimizu, H., Mogari, H., Nishida, N., Hirota, N., Furuno, A., Kudo, Y., Baba, M., Baba, N., Cheng, J., Fujimoto, T., Ishihara, N., Ortiz-Sandoval, C., Barlow, L. D., Raturi, A., Dohmae, N., Wakana, Y., Inoue, H., Tani, K., Dacks, J. B., Simmen, T., and Tagaya, M. A Role for the Ancient SNARE Syntaxin 17 in Regulating Mitochondrial Division. Dev. Cell 32, 304-317 (2015) [PubMed]

Kiyoko Fukami

1.
Nakamura, Y., Kanemaru, K., Kojima, R., Hashimoto, Y., Marunouchi, T., Oka, N., Ogura, T., Tanonaka, K., and Fukami, K. Simultaneous loss of phospholipase Cδ1 and phospholipase Cδ3 causes cardiomyocyte apoptosis and cardiomyopathy. Cell Death & Dis. 5,1215 (2014) [PubMed]
2.
Ishida, S., Matsu-ura, T., Fukami, K., Michikawa, T., and Mikoshiba, K. Phospholipase C-β1 and β4 contribute to non-genetic cell-to-cell variability in histamine-induced calcium signals in HeLa cells. PloS One. 9, 86410 (2014) [PubMed]
3.
Yamaguchi, H., Yoshida, N., Takanashi, M., Ito, Y., Fukami, K., Yanagihara, K., Yashiro, M., and Sakai, R. Stromal fibroblasts mediate extracellular matrix remodeling and invasion of scirrhous gastric carcinoma cells. PloS One. 9, 85485 (2014) [PubMed]
4.
Yamaguchi, H., Takanashi, M., Yoshida, N., Ito, Y., Kamata, R., Fukami,K., Yanagihara, K., and Sakai, R. Saracatinib impairs the peritoneal dissemination of diffusetype gastric carcinoma cells resistant to Met and FGFR inhibitors. Cancer Sci. 10, 12387 (2014) [PubMed]
5.
Satow, R., Hirano, T., Batori, R., Nakamura, T., Murayama, Y., and Fukami, K. Phospholipase C delta 1 induces E-cadherin expression and suppresses malignancy in colorectal cancer cells. Proc. Natl. Acad. Sci. USA. 111, 13505-13510 (2014) [PubMed]
6.
Inagaki, T., Iwasaki, S., Matsumura, Y., Kawamura, T., Tanaka, T., Abe, Y., Yamasaki, A., Tsurutani, Y., Yoshida, A., Chikaoka, Y., Nakamura, K., Magoori, K., Nakaki, R., Osborne., F. T, Fukami, K., Aburatani, H., Kodama, T., and Sakai, J. The FBXL10/KDM2B Scaffolding Protein Associates with Novel Polycomb Repressive Complex-1 to Regulate Adipogenesis. J. Biol. Chem. 290, 4163-77 (2015) [PubMed]
7.
Abe, Y., Rozqie, R., Matsumura, Y., Kawamura, T., Nakaki, R., Tsurutani, Y., Tanimura-Inagaki, K., Shiono, A., Magoori, K., Nakamura, K., Ogi, S., Kajimura, S., Kimura, H., Tanaka, T., Fukami, K., Osborne, T., Kodama, T., Hiroyuki Aburatani, Inagaki, T., and Sakai, J. JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis, Nature Commun. in press [PubMed]
8.
Kanemaru, K., Matsuyuki, A., Nakamura, Y., and Fukami, K. Obesity exacerbates imiquimod-induced psoriasis-like epidermal hyperplasia and interleukin 17 and interleukin 22 production in mice. Exp. Dermatol in press. [PubMed]

Masato Tanaka

1.
Karasawa K, Asano K, Moriyama S, Ushiki M, Monya M, Iida M, Kuboki E, Yagita H, Uchida K, Nitta K, Tanaka M. Vascular‐resident CD169‐positive Monocytes and Macrophages Control Neutrophil Accumulation in the Kidney with Ischemia‐reperfusion Injury. J. Am. Soc. Nephrol. Apr;26(4):896-906. 2015 [PubMed]
2.
Yonekawa, A., Saijo, S., Hoshino, Y., Miyake, Y., Ishikawa, E., Suzukawa, M., Inoue, H., Tanaka M., Yoneyama, M., Oh-Hora, M., Akashi, K., and Yamasaki, S. Dectin-2 Is a Direct Receptor for Mannose-Capped Lipoarabinomannan of Mycobacteria. Immunity. 41(3):402-13.2014 [PubMed]
3.
Taguchi K, Okada A, Kitamura H, Yasui T, Naik T, Hamamoto S, Ando R, Mizuno K, Kawai N, Tozawa K, Asano K,Tanaka M, Miyoshi I, Kohri K. Colony-Stimulating Factor-1 Signaling Suppresses Renal Crystal Formation. J. Am. Soc. Nephrol. 25(8) : 1680-1697, 2014 [PubMed]
4.
Ravishankar B, Shinde R, Liu H, Chaudhary K, Bradley J, P. Lemos H, Chandler P, Tanaka M, Munn DH, Mellor AL, McGaha L, Marginal zone CD169+ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance. Proc Natl Acad Sci USA. 111(11):4215-4220, 2014 [PubMed]